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Vision and Mission

Minimize the impact of pain on humanity by enabling fast, safe, and precise treatment for millions of patients through groundbreaking inhalation technology.

Redefining Pain Medicine

Syqe is a MedTech company transforming the future of pain management through precision inhaled therapeutics.
Our proprietary technology platform enables pharmaceutical-grade drug delivery with unparalleled accuracy, consistency, and safety redefining how chronic pain is treated.
Patients and healthcare professionals are already using Syqe’s technology, demonstrating measurable improvement in pain relief and quality of life.
In parallel, the company is conducting a global clinical trial to validate the therapeutic efficacy further and support regulatory expansion into additional markets.
By combining advanced engineering, clinical excellence, and patient-centered innovation, Syqe is setting a new global standard for precision pain medicine, measurable, scalable, and sustainable.

THE FUTURE OF MEDICINE

The safest and most precise drug inhalation technology

The Unmet Need: A Global Pain Crisis

Chronic pain is recognized by the World Health Organization (WHO) as one of the leading causes of long-term disability worldwide [1].
According to recent epidemiological data, over one billion people suffer from chronic pain, and more than 400 million experience moderates to severe pain on a daily basis
[2].

Chronic pain is frequently accompanied by sleep disturbances, depression, and reduced cognitive function, deeply impacting quality of life and productivity
[3].
Unlike acute pain, which serves as a physiological alarm system, chronic pain is maladaptive a pathological rewiring of the central nervous system.
Neuroscientific studies have shown that prolonged exposure to pain leads to central sensitization, a state where the spinal cord and brain amplify pain signalling, causing the sensation of pain even in the absence of actual tissue damage
[4].
This process, often described as pain memory, transforms pain from a symptom into a chronic neurological condition.
Despite the wide availability of pharmacological treatments including opioids, anticonvulsants, and antidepressants most patients report inadequate or inconsistent relief.

Clinical studies indicate that over 60% of chronic pain patients discontinue their treatment within six months due to limited efficacy or side effects such as sedation, dependency, or gastrointestinal issues [5].
As a result, chronic pain remains a global medical and economic burden, costing an estimated $560–$635 billion annually in the United States alone more than heart disease, cancer, and diabetes combined
[6].

This massive unmet need highlights the urgency for innovative, evidence-based solutions that provide effective, safe, and personalized pain relief.
Sources

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Why Syqe

Since 2011 – Pioneering Innovation in Chronic Pain Treatment

For over a decade, Syqe has been redefining the standards of pain management through innovation, science, and real-world clinical impact.

Our metered-dose inhalation platform is the only one of its kind, enabling physicians to prescribe plant-based medicine with pharmaceutical precision, safety, and predictability.

Syqe’s technology has been clinically validated, demonstrating rapid onset of action, precise micro-dosing accuracy, and an exceptional safety profile across multiple studies and real-world settings.

With regulatory approvals including CE (Europe), ARTG (Australia), MDL (Canada), EU-GMP, and IMC-GMP, our platform meets the highest global pharmaceutical and manufacturing standards.

Operating commercially in Israel and Australia, Syqe has treated thousands of patients and built a unique Real-World Evidence (RWE) database that continuously supports clinical innovation and regulatory advancement.

Our commercial collaborations with the Israeli Ministry of Defense, National Insurance Institute, and the Australian Veterans Affairs reflect growing institutional trust in the safety, efficacy, and scalability of our solution.

Together, these achievements position Syqe at the forefront of precision inhalation medicine—transforming the way chronic pain is managed worldwide.

Clinical Progress in Europe

Clinical Progress

DPNP (Diabetic Peripheral Neuropathic Pain)

Preclinical

Phase 1

Phase 2

Phase 3

Filed for registration

PTSD (Post-Traumatic Stress Disorder)

Preclinical

Phase 1

Phase 2

Phase 3

Filed for registration

Lumbar Pain (Lower Back Pain)

Preclinical

Phase 1

Phase 2

Phase 3

Filed for registration

Insomnia

Preclinical

Phase 1

Phase 2

Phase 3

Filed for registration

Our Team

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WE TURN SCIENCE INTO IMPACT

120

Employees

6

Core Team

200

Patents

100

Partners

Career

We Care Deepl

We care about people. This defines us, and we stop at nothing in our journey to make people’s lives better

We Are Creators

We grow by envisioning, doing, and solving daring to push boundaries and create new realities

We Achieve Together

We have each other’s backs our openness and collaboration empower us to achieve more together

We Are Free to Be

To be our true selves, our differences inspire us and make Syqe an exciting, creative place to belong

Join us in redefining how medicine is delivered

At Syqe, we’re redefining how the world delivers and experiences medicine.
Our mission is to transform pain treatment through science, precision, and purpose — creating technology that empowers patients and elevates standards of care. We believe that compassion and engineering can coexist, designing solutions that give people control, dignity, and freedom from pain.
Join us in shaping the future of precision inhalation therapy where your talent truly makes a difference.

Contact Us

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